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異櫻花亭 |
| CAS No.: |
480-43-3 |
| 分子式： |
C16H14O5 |
| 分子量： |
286.2794 |
| 備注： |
中文名稱異櫻花亭中文同義詞異櫻花亭;異櫻花亭(異櫻花亭苷);異櫻花亭(異櫻花素);5,7-二羥基-4’-甲氧基黃烷酮;異野櫻素;異櫻花亭苷;異櫻花素;異櫻花素,異櫻花亭(異櫻花亭苷)英文名稱ISOSAKURANETIN英文同義詞5,7-DIHYDROXY-4’-METHOXYFLAVANONE;ISOSAKURANETIN;(S)-2,3-dihydro-5,7-dihydroxy-2-(4-methoxyphenyl)-4-benzopyrone;ISOSAKURANETIN(P);5,7-DIHYDROXY-4’’-METHOXYFLAVANONEhplc;ISOSAKURANETINWITHHPLC;(2S)-5,7-Dihydroxy-4’-methoxyflavanone;(S)-2,3-Dihydro-2-(4-methoxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-oneCAS號480-43-3分子式C16H14O5分子量286.28EINECS號207-551-8相關類別對照品標準品;對照品;中藥對照品;植物提取物;標準品;分析試劑標準品;對照品-中藥對照品;黃酮;標準品-中藥標準品;標準品，對照品;Flavanones;FlavonoidsMol文件480-43-3.mol結構式異櫻花亭性質熔點193-194°C沸點539.2±50.0°C(Predicted)密度1.370±0.06g/cm3(Predicted)溶解度DMSO：125mg/mL（436.64mM；需要超聲波和加熱）酸度系數(pKa)7.50±0.40(Predicted)形態(tài)粉末顏色白色LogP3.840(est)異櫻花亭用途與合成方法產品描述異櫻花亭是一種白色針晶(氯仿-甲醇)，溶于氯仿、甲醇、丙酮、乙酸乙酯、DMSO。紫外燈365nm下顯綠色熒光，鹽酸鎂粉反應呈陽性，濃硫酸-香草醛反應顯橙紅色。生物活性Isosakuranetin是可以在Citrusbergamia的果實中找到的黃烷酮黃酮類化合物。體外研究IsosakuranetinstimulatesmelaChemicalbookninaccumulationinadose-dependentmanner.Inaddition,Isosakuranetinat30μMgraduallyincreasestheexpressionofTyr,TRP1,andTRP2after48and72h.TheMTTassayshowsthatIsosakuranetindecreasesthenumberofcellsatconcentrationsgreaterthan45μM.FurtheranalysisoftrypanbluestainingdemonstratesthatIsosakuranetindoesnotaffecttheviabilityofB16melanocytes,butshowsthatIsosakuranetindecreasestheirproliferationrate.ThetyrosinaseactivityofB16melanocytestreatedwith15and30μMIsosakuranetinfor72hissignificantlyincreasedby2-and3.2-fold,respectively,incomparisonwiththatofthecontrolcells.體內研究Isosakuranetindose-dependentlyincreasesthepaw-withdrawalthresholdwithinthedoserangeof1.5to6mg/kg.PosthocanalysisrevealsthatIsosakuranetinincreasesthepaw-withdrawalthresholdandstatisticalsignificanceisseenattimes30and40minforthedoseof3mg/kgand30to60minforthedoseof6mg/kg.化學性質黃色結晶性粉末，可溶于甲醇、乙醇、DMSO等有機溶劑，來源于飛機草，薔薇科櫻屬植物櫻花Prunusserrulata。用途用于含量測定/鑒定/藥理實驗等。 |
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